Methods:Thre e hundred men were examined for signs and symptoms of prostate dis orders.147patients with a digital rectal examination indicating a positive result underwent a pros tate-s pecificantigen(PSA)test.A biopsy was advised for 103 of the men,of whom 50 completed the s tudy.Be fore undergoing biopsy,an examination with the EIS(e le ctro interstitial scan)system usingbioimpedance and chronoamperometry was pe rfo rme d.In reference to the biopsy results(negativeor positive),a statistical analysis of the EIS data and PSA was conducted using receiver operatingcharacte ris tic curve s to de te rmine the specificity and sensitivity of each test. Res ults:The PSA test had a sensitivity of 73.9%and specificity of 51.9%using a cutoff value>4and a sensitivity of 52.2%and specificity of 81.5%using a cutoff value≥5.7 and P=0.03.The deltaof the electrical conductivity(DE)of the left foot-right foot pathway had a sensitivity of 62.5%andspecificity of 85.2%,with a cutoff value≤-5 andP=0.0001.Algorithms comprising the delta ofelectrical conductivity and PSA showed a sensitivity of 91.5%and a specificity of 59.3%,with acutoff value≤-10.52 andP=0.0003. Conclusion:The EIS system had a ve ry good specificity of 85.2%.Howe ve r,the sensitivity of 62.5%wo uld be a pro ble m.Using a PSA reference.4.1 ng/mL,the adjunctive use of bioimpedance and chronoamperometry provided by EIS technology could raise the s e ns itivity from 73.9%to 91.5%and the specificity from 51.9%to 59.3%in prostate cancer screening. 结论：鹰演E.I.S系统具有很好的特异性为85.2%，通过EIS技术提供了生物电阻抗法的辅助使用，可在前列腺癌筛查中将特异性灵敏度从73.9%到91.5%和从51.9%到59.3%。 鹰演检测在健康评估中的应用及价值 鹰演检测测试有脂肪肝或者脂肪肝倾向的人群与腹部彩色多普勒超声提示有轻度至重度脂肪肝人群比较，差异无统计学意义（P>0.05）,血糖血脂肿瘤标记物检测比较，差异无统计意义 （P>0.05）。（1）鹰演检测结果脂肪肝273例（58.5%）血糖升高290例（59.3%），无肿瘤风险360例（89.3%）。（2）腹部彩超结果脂肪肝227例（56.3%）。（3）血生化检查血糖升高280例（69.5%）血脂升高230例（57.1%），符合空腹血糖>5.5mmol/L：总胆固醇，三酰甘油低脂肪胆固醇任意一项高于正常上限。（4）肿瘤标记物检测各项均（-）无肿瘤风险358例（88.8%）。 另外，在以上403例中，共有147符合代谢综合征诊断标准（2001年，美国“国家胆固醇教育计划”成年人治疗组3次报告中提出工作定义），且行生物能清肝排毒和强化生活方式管理，3个月后复查鹰演检测及腹部彩超多普勒超声，血糖，血脂，腹部彩超多普勒超声显示脂肪肝程度减轻患者鹰演检测均显示肝脏功能好转，血生化检查提示血糖血脂下降患者，复查鹰演检测提示干汤圆生成减少胰岛功能改善血脂下降对比符合率100%。结论：鹰演E.I.S在肿瘤检测的筛查中，检出无肿瘤风险360例（89.3%）对比常规肿瘤标记物检出无肿瘤风险358例（88.8%），一致性达到99.4%以上，且阴性检出率*高。 文献出处：张于东，《中华保健医学杂志》，2013全军保健医学学术研讨会中国科技核心期刊，国家科技统计源期刊
